Clinical Significance :
SLO is a toxic immunogenic exoenzyme produced by ß-haemolytic streptococci of group A, C, and G. Measuring the ASO antibodies are useful for the diagnosis of rheumatoid fever, acute glomerulonephritis and streptococcal infections. Rheumatic fever is an inflammatory disease affecting connective tissue from several parts of human body as skin, heart, joints etc. and acute glomerulo-nephritis is a renal infection that affects mainly to renal glommerulus.
Clinical Significance :
Rheumatoid factor is present in the serum of approximately 70-80% of patients with rheumatoid arthritis. The highest titers are often found in severe cases of rheumatoid arthritis. Rheumatoid arthritis is an inflammatory and degenerative condition involving multiple organ systems, especially the connective tissue structures and synovial joints. This condition is characterized by an inflammatory reaction in the synovial membrane resulting in swelling and pain in the joints.
Clinical Significance:
A bilirubin test measures the levels of bilirubin in your blood. Bilirubin (bil-ih-ROO-bin) is a yellowish pigment that is made during the normal breakdown of red blood cells. Bilirubin passes through the liver and is eventually excreted out of the body.
Higher than normal levels of bilirubin may indicate different types of liver or bile duct problems. Occasionally, higher bilirubin levels may be caused by an increased rate of destruction of red blood cells (hemolysis).
Clinical Significance :
This test measures the level of uric acid in the blood.Uric acid measurements are used in the diagnosis and treatment of numerous renal and metabolic disorders, including renal failure, gout, leukemia, psoriasis, starvation or other wasting conditions and in the treatment of patients receiving cytotoxic drugsThe American College of Rheumatology published guidelines on the management of gout in 2012 that recommend that target serum urate (uric acid) levels should be below 6 mg/dL for people diagnosed with the condition.