Decreased serum calcium values are found in hypoparathyroidism, rickets, osteiomalacia and steatorrhea. A fall in serum calcium can occun in acute pancreatitis and in those forms of renal disease in which excessive proteinuria is observed. Increased serum calcium values are observed in hyperparathyroidism, hypervitamonosis D and multiple myeloma.
Uric acid is the end product of nucleoprotein metabolism. It is a low threshold excretory product. the serum uric acid level is ofter raised in gout. the determination has diagnostic value differentiating gout from non gout arthritis. uric acid levels are also increased in renal failure, uremia and leukemia.
Elevated levels of blood urea nitrogen are observed in pre renal , renal and post renal conditions .
Pre renal conditions .. diabetes mellitius, dehydration, cardiac failure , hematemesis, severe burns, high fever etc..
Renal conditions.. disease of kidneys.
Post renal conditions.. inlargement of prostate, stones in the urinary tract, tumor of the bladder . Decreased values have been reported in severe liver disease, protein malnutrition & pregnency.