Decreased serum calcium values are found in hypoparathyroidism, rickets, osteiomalacia and steatorrhea. A fall in serum calcium can occun in acute pancreatitis and in those forms of renal disease in which excessive proteinuria is observed. Increased serum calcium values are observed in hyperparathyroidism, hypervitamonosis D and multiple myeloma.
NOTE :- Lipid profile range as per ncep – atp 111 are :
Serum cholestrol (Total) :
Desirable: < 200 mg/dl, Borderline: 200-239 mg/dl, Elevated : >250 mg/dl.
Serum high – density lipoprotein cholterol (HDL):
Desirable: > 60 mg/dl, Borderline: 40-60 mg/dl, Elevated : >70 mg/dl.
TOTAL cholestrol : HDL cholestrol:
Low risk : 3.3 - 4.4, Average risk : 4.4 – 7.1, Moderate risk : 7.1 – 11.0, High risk : >11.0
Serum low – density lipoprotein (LDL) cholesterol:
Desirable : < 100 mg/dl, Borderline: 100-159 mg/dl, Elevated : >160 mg/dl.
* It is ptreferable to measure lipid after 12 hrs fasting, as triglyceride levels rised and both HDL & LDL levels fall after fat containing meals.
* since serum lipid levels a vary widely from day to day( being largely dependaent on diet) , at least 2 - 3 measurments should be made days or weeks apart , before labelling a person as hyper lipidaemic/ normolipidaemic or before initiating therapy.
*Both LDL & HDL levels remains decreased for several weeks after acute inflammatory states, following myocardial infection, stress, trauma, surgery and recent illness.
* lipid profile values should always be corroborated in the light of clinical findings, dietary habits / axcess/ restrictions, effects of illness, exercise, inter & intra individual variations and drugs( Anabolic steroids, oral contraceptives) progestogens, antithypertensives, oestrogen, insulin & hydrochlorthiazide.
Method:- CLIA ( Beckman Coulter) (3rd Generation)
REFERENCE RANGE IN PREGNANCY:
| 1st Trimester : 0.10 - 2.50 µIu/Ml |
| 2nd Trimester : 0.20 - 3.00 µIu/Ml |
| 3rd Trimester : 0.30 - 3.00 µIu/Ml |
Low TSH blood test results indicate an underactive thyroid gland, that is, hypothyroidism. This means that the thyroid gland is not producing thyroid hormones to the optimum level. The pituitary gland releases more TSH hormones to stimulate the thyroid gland to produce more hormone. A high TSH level indicates some acute or chronic problems related to thyroid dysfunction. High TSH blood test results also indicate that there may be some problem with the pituitary gland. A tumor may cause high TSH levels to be secreted by the pituitary gland. Patients who have undergone thyroid gland removal surgery may also show high TSH blood tests results. This means they are not begin administered the correct dose of thyroid medication that keeps the hormone production in check. You can read more on blood test results explained.High TSH blood test results indicate an overactive thyroid gland, that is, hyperthyroidism. Also, low TSH blood test results indicate a patient is begin administered excessive doses of thyroid hormone medication, in case of hormone replacement therapy. In very rare cases, low TSH level indicate towards damage or problems with the pituitary gland.
Methodology: Sedimentation
Factors increasing ESR -Old age -Pregnancy -Anemia -Elevated fibrinogen -Macrocytosis
Factors decreasing ESR -Microcytosis -Low fibrinogen -Polycythemia -Marked leukocytosis